Lp(a) in Clinical Practice

Lipoprotein(a), or Lp(a), is a genetic form of cholesterol that increases the risk of heart attack, stroke, and aortic valve disease—even when LDL levels are normal. This short course helps health-care professionals understand when and how to test for Lp(a), interpret results, and manage elevated levels with confidence. Through four practical modules, you’ll explore the science behind Lp(a), learn to identify high-risk patients, and prepare for emerging therapies that target Lp(a) directly. Designed with insights from patients and caregivers, this toolkit supports compassionate, informed cardiovascular care.

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Overall Course Learning Objectives

After completing this course, you will be able to:

Explain Lp(a) structure, inheritance, and core mechanisms linked to ASCVD and aortic valve disease.
Identify patients who warrant Lp(a) testing using guideline-aligned clinical indications.
Order Lp(a) testing, interpret results in nmol/L or mg/dL, and communicate findings clearly to patients and families.
Integrate Lp(a) into risk management plans, including LDL lowering strategies and referral pathways.
Describe the status and clinical relevance of emerging Lp(a)-targeted therapies.